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. 2013 Mar 27;304(11):F1358–F1365. doi: 10.1152/ajprenal.00476.2012

Fig. 8.

Fig. 8.

Expression of mRNA for markers of renal inflammation in WT and CRPtg mice subjected to renal IRI. Expression of mRNA for FcγRs, markers of proinflammatory M1 macrophages [inducible nitric oxide synthase (iNOS) and TNF-α], and markers of anti-inflammatory M2 macrophages [arginase (ARG) and mannose receptor (MR)] in whole kidneys from WT (white bars) and CRPtg mice (black bars) subjected to renal IRI. Each bar represents the average mRNA expression after renal IRI, normalized to mRNA levels in sham-treated WT, and the SE is for 9 amplifications of mRNA isolated from at least 3 kidneys each. *P < 0.05, for one sample t-tests of the indicated group vs. WT/sham. #P < 0.05, for two-tailed t-tests of the indicated marker in CRPtg vs. WT. Inset: mRNA expression in kidneys of sham-treated CRPtg compared with sham-treated WT.