Fig. 1.

Renal function in experimental focal segmental glomerulosclerosis (FSGS). Renal function, as measured by urine protein:creatinine ratio, was not different in all normal age-matched animals compared with baseline before experiment. Compared with normal mice (open bars), there was an increase in the urine protein:creatinine ratio in mice with FSGS given DMSO at 2 and 4 wk (gray bars). Prednisone treatment decreased the urine protein:creatinine ratio in mice with FSGS at 2 and 4 wk (filled bars).