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NO synthase inhibition does not increase JCl when angiotensin II is removed from the bath. JCl (A) and VT (B) were measured in CCDs from aldosterone-treated mice before and after the application of the NO synthase inhibitor (100 μM l-NAME) without angiotensin II in the bath. In the absence of angiotensin II, application of l-NAME did not alter JCl or VT. Solid lines show individual tubules. Open squares show means ± SE.
