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Suppression of basal ACTH-R mRNA expression by leptin. Effects of preincubation with Lep 10 or Lep 100 on basal ACTH-R mRNA expression in adrenocortical cells from antenatal GC [Beta, male (n = 5) and female (n = 5); ■] and vehicle-treated [control, male (n = 4) and female (n = 4); □] male (A) and female (B) adult sheep. Each no. indicates no. of animals analyzed. Data are expressed as means ± SE.
