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Suppression of basal cortisol secretion by leptin. Effects of preincubation with 10 (Lep 10) or 100 ng/ml leptin (Lep 100) on basal cortisol secretion in adrenocortical cells from antenatal GC [Beta, male (n = 5) and female (n = 5); ■] and vehicle-treated [control, male (n = 5) and female (n = 6); □] male (A) and female (B) adult sheep. Each no. indicates no. of animals analyzed. Data are expressed as means ± SE. *P < 0.05 vs. control.
