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Suppression of ACTH-stimulated cortisol secretion by leptin. Effects of preincubation with Lep 10 or Lep 100 on ACTH-stimulated cortisol secretion in adrenocortical cells from antenatal GC [Beta, male (n = 4) and female (n = 4); ■] and vehicle-treated [control, male (n = 5) and female (n = 6); □] male (A) and female adult sheep (B). Each no. indicates no. of animals analyzed. Data are expressed as means ± SE. *P < 0.05 vs. control; #P < 0.05 vs. female.
