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. 2013 Apr 18;304(12):G1103–G1116. doi: 10.1152/ajpgi.00299.2012

Fig. 5.

Fig. 5.

Coexpression of ZSCAN4 with stem/progenitor cell markers in the adult human pancreas. A: coexpression of ZSCAN4 and BMI1 is shown in an oval cell between acini. Note that these oval cells exist as a single cell or sometimes a cluster of a few cells. White dotted lines indicate the margin of acini. B: CAII is expressed in centroacinar cells and oval cells. ZSCAN4 is colocalized with CAII in an oval cell. C: ZSCAN4 and ALDH1 are colocalized in an oval cell between acini. D: NEUROG3 is colocalized with ZSCAN4 in a subpopulation of acinar cells. White dotted lines indicate the margin of pancreatic acini. E: both ZSCAN4 and SSEA3 are expressed in the same oval cells. F: coexpression of ZSCAN4 with LGR5 in an oval cell with some cytoplasmic protrusions. White dotted lines indicate the margin of pancreatic acini. G: DCAMKL-1 is colocalized with ZSCAN4 in the pancreas (white arrows). H: SSEA3-positive oval cells are also positive for CD163. Bars, 25 μm.