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Increased expression of Zscan4 and other progenitor cell markers in mouse acute pancreatitis. All of the progenitor cell markers examined are upregulated in caerulein-induced mouse acute pancreatitis at day 1 (D1) but returned to the basal levels at as early as day 4 (D4) (see text). D0, control day. A: Zscan4; B: Bmi1; C: SSEA3; D: Neurog3; E: Lgr5. The no. of marker positive cells per HPF is summarized (mean ± SD, n = 3) in the panels on the right.
