Fig. 5.

Secondary structure of ABD and AD and cis-elements. A and B depict the secondary structures for ABD and AD, respectively. The sequence and the location of the two eB cis-elements is noted (A), with blue and red colors. The RNAfold online software was used to obtain the secondary structures as described in Fig. 2C. C: the cis-element identified within ABD by the matrix-based motif discovery algorithm. The ** denotes the last 6 nt of exon A that were included in the identified cis-element. The sequence in blue and red denotes the 2 eB cis-elements, the eB pseudo-loop and loop, respectively. The free energy ΔG in kcal/mol and the color scale 0 to 1 (red, most stable) are shown.