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Effect of intracellular acidosis on Epi Ito during AP clamps. A: example AP clamp experiment showing the action of intracellular acidosis (80.0 mM acetate) to reduce Ito. CL = 5 s. B: summary of results for peak Ito during AP clamps (CL = 5 s, n = 8; CL = 2 s, n = 7). **P < 0.01, paired, compared with control.
