Fig. 3.

Microarray gene expression of genes involved in cardiac hypertrophy functions in subcluster 2. The first 3 major columns on the left labeled “normal,” “SuHx,” and “SuHxCarv” denote expression in the normal, SU5416/hypoxia, and SU5416/hypoxia + carvedilol RVs. Red coloration indicates increased expression compared with the average normal RV expression level, while green indicates reduced expression. The small columns represent different animals treated with the same condition. The last major column to the right of the gray line labeled “-” denotes the difference in expression between the SU5416/hypoxia + carvedilol and SU5416/hypoxia RVs. Red coloration indicates increased expression in the SU5416/hypoxia RV with carvedilol treatment compared with an untreated SU5416/hypoxia RV, and green indicates reduced expression in the SU5416/hypoxia + carvedilol RV compared with the SU5416/hypoxia RV.