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. Author manuscript; available in PMC: 2013 Jun 13.
Published in final edited form as: Gastroenterology. 2011 Feb 13;140(5):1618–28.e16. doi: 10.1053/j.gastro.2011.02.009

Figure 5.

Figure 5

miR-517a promotes tumorigenesis in vivo. (A) Luciferase-tagged Huh7 cells transduced with miR-517a or control vector were injected into the left lobe of the liver of nude mice. Representative images taken at day 1, and at 2, 4, 6, and 8 weeks are displayed. (B) Incidence of liver tumors in mice injected with Huh7 transduced with miR-517a or control vector. (C) Kaplan–Meier curves representing the decrease in survival of mice injected with miR-517a–expressing Huh7 compared with control-Huh7. (D) Multiple tumor nodules were observed in liver of mice administered with miR-517a–transduced Huh7.