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. 2013 Jun 13;3:1986. doi: 10.1038/srep01986

Figure 3. Behavioral tests.

Figure 3

MST-KO mice (#44-H-1-6, 44-H-1-7, 44-H-1-8, 44-H-2-3, 44-H-2-4, 44-H-2-5, 44-H-2-11, 44-H-2-12, 44-H-2-13, 44-H-3-3-1, 44-H-3-3-2, 44-H-3-3-3, 44-H-3-7, 44-H-3-8, 44-H-3-9, 44-H-3-13, and 44-H-3-14 obtained from 6 different parents) showed anxiety-like behaviors (a–h). (a–d) Open field test (OF) (in Fig. 3d, p values of data from 1 to 15 min between MST-KO and control groups are 3.851 × 10−5, 0.1001, 0.0240, 0.8534, 0.0290, 0.1822, 0.0373, 0.3342, 0.0113, 0.4355, 0.500, 0.5284, 0.9876, 0.3265, and 0.3905, respectively). (e, f) Light/Dark transition test (L/D). (g, h) Elevated plus-maze test (EPM). (i) 3-chambered social interaction tests (3CSI) to examine social behavior. The values of white bars represent the interaction time with empty cage. The values of gray bars represent the interaction time with the cage in which a stranger mouse resides. (j) Forced swim tests (FST) for depressiveness. All data represent the mean ± S.E.M (bar). *, p < 0.05; ***, p < 0.001; Cont, control mice; KO, homozygous (null) KO mice.

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