[Table/Fig-3]:
Medication considered safe during pregnancy
| Drugs | FDA category | Use in pregnancy | Use in nursing | Possible side effects |
|---|---|---|---|---|
| Analgesics | ||||
| Acetaminophen | B | Yes | Yes | Not reported |
| Aspirin | C | Not in 3rd trimester | No | Postpartum haemorrhage |
| Ibuprofen | B | Not in 3rd trimester | Yes | Delayed labour |
| aproxen | B/D** | Not in 2nd ½ of pregnancy | Yes | Delayed labour |
| Codeine | C | With caution | Yes | Multiple birth defects |
| Oxycodone | B | With caution | With Caution | NRD |
| Hydrocodone | C/D* | With caution | With Caution | NRD |
| Morphine | B | Yes | Yes | Respiratory depression |
| Propoxyphene | C | With caution | Yes | Not reported |
| Meperidine | B | Yes | Yes | Not reported |
| Pentazocine | C | With caution | With Caution | Not reported |
| Antibiotics | ||||
| Amoxicillin | B | Yes | Yes | Not reported |
| Metronidazole | B | Yes | Yes | Not reported |
| Erythromycin | B | Yes | Yes | Not reported |
| Penicillin v | B | Yes | Yes | Not reported |
| Cephalosporins | B | Yes | Yes | Not reported |
| Gentamycin | C | Yes | Yes | Fetal ototoxicity |
| Clindamycin | B | Yes | Yes | Not reported |
| Tetracycline | D | No | No | Maternal toxicity/ |
| Fetal death | ||||
| Chloramphenicol | X | No | No | Not reported |
| Chlorhexidine | B | No data | No data | Fetal toxicity |
| Antifungals | ||||
| Nystatin | B | Yes | Yes | Not reported |
| Clotrimazole | B | Yes | Yes | Not reported |
| Fluconazole | C | With Caution | With Caution | Not reported |
| Ketoconazole | C | With Caution | No | Fetal Bradycardia |
| Local Anesthetics | ||||
| Lidocaine | B | Yes | Yes | Not reported |
| Mepivacaine | C | With Caution | Yes | Fetal Bradycardia |
| Prilocaine | B | Yes | Yes | Not reported |
| Bupivacanine | C | With Caution | Yes | Fetal Bradycardia |
| Etidocaine | B | Yes | Yes | Not reported |
| Corticostroids | ||||
| Prednisolone | B | Yes | Yes | Not reported |
| Sedative/Hypnotics | ||||
| Nitrous oxide | Not assigned | Not in 1st trimester (**) | Yes | Spontaneous abortions |
| Barbiturate | D | Avoid | No | NRD |
| Benzodiazepines | D | No | No | Cleft lip/palate |
* D- indicates caution,if used for prolonged period of time or high doses.
** NRD- Neonatal Respiratory Depression.