Table 1.
Rank | Code | Description | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | Total | % | BPR |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Q369 | Cleft lip, unilateral | 208 | 195 | 137 | 112 | 143 | 138 | 126 | 1059 | 6.35 | 4.57 |
2 | Q249 | Congenital malformation of heart, unspecified | 131 | 119 | 143 | 177 | 139 | 132 | 135 | 976 | 5.85 | 4.21 |
3 | Q039 | Hydrocephalus | 113 | 0 | 163 | 130 | 173 | 135 | 161 | 875 | 5.25 | 3.77 |
4 | Q909 | Down’s syndrome | 109 | 137 | 127 | 127 | 122 | 134 | 102 | 858 | 5.14 | 3.70 |
5 | Q250 | Patent ductus arteriosus | 68 | 95 | 55 | 69 | 68 | 95 | 57 | 507 | 3.04 | 2.19 |
6 | Q059 | Spina bifida, unspecified | 88 | 117 | 64 | 53 | 66 | 55 | 54 | 497 | 2.98 | 2.14 |
7 | Q359 | Cleft palate, unilateral | 71 | 64 | 71 | 54 | 45 | 67 | 70 | 442 | 2.65 | 1.91 |
8 | Q400 | Congenital hypertrophic pyloric stenosis | 62 | 66 | 36 | 53 | 66 | 61 | 64 | 408 | 2.45 | 1.76 |
9 | Q750 | Craniosynostosis | 38 | 34 | 40 | 78 | 62 | 61 | 90 | 403 | 2.42 | 1.74 |
10 | Q899 | Congenital malformation, unspecified | 39 | 24 | 59 | 113 | 68 | 70 | 24 | 397 | 2.38 | 1.71 |
11 | Q205 | Discordant atrioventricular connection | 95 | 108 | 37 | 38 | 33 | 30 | 49 | 390 | 2.34 | 1.68 |
12 | Q379 | Unspecified cleft palate with unilateral cleft lip | 39 | 56 | 51 | 57 | 71 | 61 | 31 | 366 | 2.19 | 1.58 |
13 | Q423 | Imperforate anus | 47 | 58 | 38 | 37 | 24 | 41 | 40 | 285 | 1.71 | 1.23 |
14 | Q539 | Undescended testicle, unspecified | 33 | 26 | 37 | 29 | 57 | 59 | 39 | 280 | 1.68 | 1.21 |
15 | Q170 | Microtia | 6 | 26 | 32 | 51 | 40 | 50 | 71 | 276 | 1.65 | 1.19 |
16 | Q439 | Congenital malformation of intestine, unspecified | 32 | 39 | 38 | 38 | 38 | 46 | 42 | 273 | 1.64 | 1.18 |
17 | Q663 | Other congenital varus deformities of feet | 60 | 32 | 30 | 27 | 31 | 41 | 51 | 272 | 1.63 | 1.17 |
18 | Q699 | Polydactyly, unspecified | 39 | 39 | 27 | 31 | 40 | 46 | 36 | 258 | 1.55 | 1.11 |
19 | Q652 | Congenital luxation of the hip | 21 | 42 | 37 | 36 | 22 | 29 | 37 | 224 | 1.34 | 0.97 |
20 | Q390 | Atresia of esophagus without fistula | 26 | 43 | 25 | 25 | 36 | 33 | 27 | 215 | 1.29 | 0.93 |
21 | Q212 | Atrioventricular septal defect | 10 | 15 | 18 | 20 | 27 | 82 | 33 | 205 | 1.23 | 0.88 |
22 | Q999 | Chromosomal abnormality, unspecified | 11 | 16 | 9 | 33 | 30 | 103 | 3 | 205 | 1.23 | 0.88 |
23 | Q043 | Other reduction deformities of brain | 8 | 38 | 35 | 32 | 37 | 22 | 25 | 197 | 1.18 | 0.85 |
24 | Q381 | Ankyloglossia | 20 | 15 | 21 | 25 | 19 | 34 | 53 | 187 | 1.12 | 0.81 |
25 | Q793 | Gastroschisis | 9 | 14 | 32 | 29 | 29 | 43 | 26 | 182 | 1.09 | 0.78 |
26 | Q248 | Other specified congenital malformations of heart | 15 | 33 | 24 | 13 | 11 | 65 | 9 | 170 | 1.02 | 0.73 |
27 | Q668 | Clubfoot NOS (not otherwise specified) | 24 | 19 | 21 | 26 | 32 | 20 | 21 | 163 | 0.98 | 0.70 |
28 | Q213 | Tetralogy of Fallot | 17 | 32 | 16 | 9 | 29 | 25 | 21 | 149 | 0.89 | 0.64 |
29 | Q658 | Other congenital deformities of hip | 17 | 22 | 15 | 31 | 12 | 32 | 16 | 145 | 0.87 | 0.63 |
30 | Q419 | Congenital absence, atresia and stenosis of small intestine, part unspecified | 13 | 21 | 29 | 17 | 25 | 27 | 12 | 144 | 0.86 | 0.62 |
31 | Q211 | Atrial septal defect | 0 | 12 | 10 | 23 | 24 | 34 | 35 | 138 | 0.83 | 0.59 |
32 | Q02 | Microcephaly | 6 | 14 | 22 | 28 | 16 | 16 | 36 | 138 | 0.83 | 0.59 |
33 | Q660 | Talipes equinovarus | 10 | 25 | 19 | 11 | 18 | 9 | 36 | 128 | 0.77 | 0.55 |
34 | Q019 | Encephalocele | 7 | 15 | 14 | 14 | 14 | 29 | 18 | 111 | 0.67 | 0.48 |
35 | Q790 | Congenital diaphragmatic hernia | 15 | 10 | 16 | 13 | 20 | 13 | 22 | 109 | 0.65 | 0.47 |
36 | Q410 | Congenital absence, atresia and stenosis of duodenum | 13 | 11 | 12 | 9 | 15 | 17 | 27 | 104 | 0.62 | 0.45 |
37 | Q203 | Transposition of great vessels | 18 | 17 | 12 | 12 | 10 | 19 | 11 | 99 | 0.59 | 0.43 |
38 | Q212 | Atrioventricular septal defect | 0 | 23 | 10 | 16 | 14 | 17 | 16 | 96 | 0.58 | 0.41 |
39 | Q897 | Multiple congenital malformations, not elsewhere classified | 11 | 12 | 15 | 18 | 9 | 20 | 9 | 94 | 0.56 | 0.41 |
40 | Q031 | Atresia of foramina of Magendie and Luschka | 33 | 21 | 12 | 15 | 0 | 7 | 0 | 88 | 0.53 | 0.38 |
41 | Q792 | Exomphalos | 9 | 12 | 15 | 11 | 13 | 17 | 11 | 88 | 0.53 | 0.38 |
42 | Q228 | Other congenital malformations of tricuspid valve | 10 | 13 | 25 | 10 | 13 | 11 | 5 | 87 | 0.52 | 0.38 |
43 | Q431 | Hirschsprung’s disease | 17 | 9 | 15 | 7 | 10 | 11 | 16 | 85 | 0.51 | 0.37 |
44 | Q620 | Congenital hydronephrosis | 7 | 15 | 17 | 14 | 21 | 9 | 83 | 0.50 | 0.36 | |
45 | Q054 | Unspecified spina bifida with hydrocephalus | 15 | 14 | 13 | 8 | 13 | 3 | 15 | 81 | 0.49 | 0.35 |
46 | Q000 | Anencephaly | 10 | 11 | 12 | 14 | 17 | 8 | 8 | 80 | 0.48 | 0.34 |
47 | Q378 | Unspecified cleft palate with bilateral cleft lip | 7 | 8 | 19 | 13 | 7 | 11 | 7 | 72 | 0.43 | 0.31 |
48 | Q224 | Congenital tricuspid stenosis | 16 | 11 | 10 | 8 | 13 | 7 | 6 | 71 | 0.43 | 0.31 |
49 | Q223 | Other congenital malformations of pulmonary valve | 2 | 0 | 0 | 0 | 19 | 44 | 2 | 67 | 0.40 | 0.29 |
50 | Q255 | Atresia of pulmonary artery | 12 | 13 | 11 | 8 | 6 | 8 | 7 | 65 | 0.39 | 0.28 |
| ||||||||||||
Subtotal | 1687 | 1811 | 1729 | 1825 | 1860 | 2159 | 1821 | 12892 | 77 | 55.58 | ||
Remain birth defects | 460 | 702 | 511 | 442 | 624 | 605 | 543 | 3887 | 23 | 16.76 | ||
Overall | 2147 | 2513 | 2240 | 2267 | 2484 | 2764 | 2364 | 16779 | 100 | 72.33 |
Notes: BPR = birth prevalence rate calculated with 2,319,737 births in the 7 years analyzed; BPR by 10,000 total births.