Table 9.
Association of integrin α2β1 genotype (ITGA2) and eNOS genotype with the type of diabetic retinopathy (DR)
| Parameters | DR patients (n = 50) | χ2 | OR (95% CI) | P value | |||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| NPDR (n = 25) | PDR (n = 25) | ||||||
|
|
|
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| n | % | n | % | ||||
| ITGA2 genotype | |||||||
| +/+ | 9 | 36.0 | 9 | 36.0 | 0.67 | 0.60 (0.11–3.30) | >0.05 |
| +/− | 11 | 44.0 | 13 | 52.0 | 0.51 (0.10–2.62) | ||
| −/− | 5 | 20.0 | 3 | 12.0 | – | ||
| eNOS genotype | |||||||
| GG | 5 | 20.0 | 8 | 32.0 | 1.23 | 0.38 (0.06–2.30) | >0.05 |
| GT | 15 | 60.0 | 14 | 56.0 | 0.64 (0.13–3.20) | ||
| TT | 5 | 20.0 | 3 | 12.0 | – | ||
Abbreviations: χ2, chi-squared test; CI, confidence interval; NPDR, nonproliferative diabetic retinopathy; OR, odds ratio; PDR, proliferative diabetic retinopathy.