Table 1.
Diffusion Tensor Parameter Values in Selected Regions of Interest of Control and Endotoxin Rabbit Kits at Postnatal Day 1a
ROIs | Group | e1 (10–3 mm2/s) | e23 (10–3 mm2/s) | ADC (10–3 mm2/s) | FA |
---|---|---|---|---|---|
Corpus callosum | Control | 1.81 (1.78-1.84) | 0.68 (0.64-0.71 | 1.06 (1.03-1.08) | 0.56 (0.55-0.57) |
Endotoxin | 1.68c (1.66-1.70) | 0.76 (0.66-0.87) | 1.07 (0.99-1.14) | 0.48b (0.42-0.54) | |
Anterior commissure | Control | 1.76 (1.67-1.84) | 0.69 (0.67-0.72) | 1.05 (1.01-1.08) | 0.54 (0.51-0.58) |
Endotoxin | 1.57c (1.52-1.63) | 0.78c (0.73-0.82) | 1.04 (1.00-1.08) | 0.43c (0.40-0.46) | |
Internal capsule | Control | 1.56 (1.52-1.61) | 0.74 (0.71-0.77) | 1.02 (0.99-1.04) | 0.44 (0.42-0.46) |
Endotoxin | 1.44c (1.35-1.52) | 0.77 (0.74-0.79) | 0.99 (0.95-1.03 | 0.38c (0.36-0.40) | |
Corona radiata | Control | 1.72 (1.69-1.75) | 0.86 (0.81-0.91) | 1.15 (1.11-1.19) | 0.42 (0.39-0.45) |
Endotoxin | 1.66b (1.62-1.70) | 0.91 (0.86-0.96) | 1.16 (1.12-1.20 | 0.37b (0.35-0.39) | |
Hippocampus | Control | 1.55 (1.40-1.69) | 1.18 (1.10-1.25) | 1.30 (1.20-1.40) | 0.18 (0.16-0.21) |
Endotoxin | 1.35b (1.28-1.43) | 1.00c (0.96-1.04) | 1.12c (1.07-1.17) | 0.20 (0.18-0.23) |
Note: ADC, apparent diffusion coefficient; FA, fractional anisotropy; ROIs, regions of interest.
Values are mean with (95% confidence interval).
P < .05
P < .005 when compared with controls.