Table 1.
Novel drugs for multiple myeloma bone disease.
| Name of the drug | Action | Bone target cell/s |
|---|---|---|
| Denosumab | RANKL neutralizing antibody | OCs |
| LY2127399 | BAFF neutralizing antibody | OCs |
| MLN3897 | CCR1 inhibitor | OCs |
| BHQ880 | DKK1 neutralizing antibody | OBs |
| ACE-011 (sotatercept) | Activin A neutralizing receptor | OCs and OBs |