Table 3.
Characteristics of Patients According to NT5C2 Mutation Status
| Variable | NT5C2 Mutated n=7 | Non-Mutated n=64 | P-value | |
|---|---|---|---|---|
| Age at Diagnosis: | Less than 10 years | 4 | 39 | 0.57 |
| ≥ to 10 years | 3 | 25 | ||
| Race: | White | 3 | 47 | 0.11^ |
| Black | 1 | 6 | ||
| Asian | 1 | 3 | ||
| Other | 1 | 5 | ||
| Unknown | 1 | 3 | ||
| Sex: | Female | 2 | 27 | 0.39 |
| Male | 5 | 37 | ||
| Cytogenetics: | ETV6/RUNX1 | 1 | 13 | 0.12# |
| Hyperdiploid | -- | 15 | ||
| E2aPBX1 | -- | 1 | ||
| Normal | 6 | 35 | ||
| Time to Relapse: | Early | 7 | 37 | 0.03 |
| Late | -- | 27 | ||
| Risk Group*: | Standard | 2 | 25 | 0.46 |
| High | 5 | 39 |
^
Fisher's Exact test p-value of all other race groups vs. white.
#
Fischer's Exact test p-value of normal vs. all other cytogenetic groups.
*
NCI risk group (Smith et al. 1996).