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Human mesenchymal stem cells reduce endotoxin-induced injury in the human lung. Photomicrographs of normal lung (left), untreated endotoxin-induced lung injury, and lung treated with mesenchymal stem cells (MSCs) or with conditioned medium (CM) from MSCs. The instillation of MSCs or its CM one hour after endotoxin injury reduced lung injury, as evidenced by reduced oedema and cellularity in the endotoxin-injured lung lobe. LPS, lipopolysaccharide. Adapted with permission from [33].
