Table 5.
Summary of animal trials that used different methods to induce intra-arrest hypothermia during cardiac arrest.
| Outcome | IATH (%) | IATH (%) | |
|---|---|---|---|
| Riter [10] | PFC-TLV | iv fluids | |
| Survival (1-hr, %) | 100 | 100 | |
| ROSC (%) | 88 | 25 | |
| CoPP (mmHg) | 14 | 8 * | |
| Yannopoulos [13] | Intravascular catheter | iv fluids | |
| ROSC (%) | 100 | 55 * | |
| CoPP (mmHg) | 21 | 15 * | |
| LVEF (%) | 32 | 17 * | |
| Yu [42] | TNEC | iv fluids | |
| Survival (%, 4 days) | 57 | 29 | |
| ROSC (%) | 100 | 29 * | |
| CoPP (mmHg) | 23 | 12 * | |
CoPP, coronary perfusion pressure; LVEF, left ventricular ejection fraction; PFC-TLV, perfluorocarbon-based total liquid ventilation; ROSC, return of spontaneous circulation; TNEC, trans-nasal evaporative cooling; *, P < 0.05