Table 1.
Group data for vascular risk factors, medication, and resting EEG data together with ANOVA statistical results
| Acute pneumonia (A) | Recovery from pneumonia (R) | Control (C) | ANOVA | |
|---|---|---|---|---|
| Age, years | 67 ± 13 | 65 ± 11 | 66 ± 8 | NS |
| Number | 43 | 24 | 30 | - |
| Female/male ratio | 30/13 | 17/7 | 16/14 | - |
| RR mean, mm Hg | 83 ± 12 | 86 ± 12 | 82 ± 14 | NS |
| Body mass index | 24 ± 6 | 28 ± 6 | 24 ± 6 | NS |
| Smoker, pack-years | 46 ± 8 | 31 ± 13 | - | NS |
| Diabetes, percentage | 17 | 14 | - | NS |
| Coronary artery disease, percentage | 44 | 29 | - | NS |
| Leukocytes, G/L | 11 ± 5 | 10 ± 4 | N.O. | NS |
| CRP, mg/dL | 95 ± 22 | 23 ± 23 | N.O. | P < 0.0001 |
| Temperature,°C | 36.7 ± 0.6 | 36.3 ± 0.3 | N.O. | NS |
| pH | 7.37 ± 0.06 | 7.40 ± 0.03 | N.O. | NS |
| Hkt, percentage | 38 ± 6 | 38 ± 5 | N.O. | NS |
| sO2 percentage | 93 ± 4 | 96 ± 4 | N.O. | P < 0.01 |
| ATS score | 2.9 ± 0.8 | 1.9 ± 0.7 | N.O. | P < 0.0001 |
| PSI score | 99 ± 27 | 86 ± 24 | N.O. | P < 0.05 |
| CURB-65 score | 1.5 ± 0.9 | 1.3 ± 0.9 | N.O. | NS |
| APACHE II score | 13 ± 4 | 11 ± 4 | N.O. | P < 0.05 |
| GCS score | 15 ± 0.5 | 15 ± 0.4 | N.O. | NS |
| ICDSC score | 3 ± 1 | 1 ± 1 | N.O. | P < 0.0001 |
| EEG μV2 delta | 82 ± 71 | 81 ± 58 | 98 ± 68 | NS |
| EEG μV2 theta | 58 ± 62 | 56 ± 52 | 26 ± 12 | C-A: P < 0.01; C-R: P < 0.01 |
| EEG μV2 alpha | 118 ± 126 | 126 ± 98 | 151 ± 128 | NS |
| EEG μV2 beta | 40 ± 25 | 44 ± 24 | 31 ± 12 | NS |
| EEG percentage delta | 30 ± 15 | 27 ± 13 | 31 ± 16 | NS |
| EEG percentage theta | 19 ± 12 | 22 ± 11 | 10 ± 3 | C-A: P < 0.001; C-R: P < 0.0001 |
| EEG percentage alpha | 35 ± 17 | 35 ± 13 | 47 ± 20 | C-A: P < 0.01; C-R: P < 0.05 |
| EEG percentage beta | 16 ± 7 | 16 ± 9 | 12 ± 5 | C-A: P < 0.05 |
| EEG peak Hz delta | 1.2 ± 0.3 | 1.2 ± 0.4 | 1.2 ± 0.3 | NS |
| EEG peak Hz theta | 6.6 ± 0.9 | 7.1 ± 0.7 | 6 ± 0.8 | C-A: P < 0.001; C-R: P < 0.0001 A-R: P < 0.05 |
| EEG peak Hz alpha | 9.4 ± 0.9 | 9.1 ± 0.8 | 11 ± 0.8 | C-A: P < 0.0001; C-R: P < 0.0001 |
| EEG peak Hz beta | 15.9 ± 2 | 15.6 ± 2.1 | 15.9 ± 2.2 | NS |
Data are presented as mean ± standard deviation unless otherwise indicated. ANOVA, analysis of variance; APACHE II, Acute Physiology and Chronic Health Evaluation II; ATS, American Thoracic Society Scale; CRP, C-reactive protein; CURB-65, confusion of new onset (defined as an abbreviated mental test score of 8 or less), urea of greater than 7 mmol/L (19 mg/dL), respiratory rate of 30 breaths per minute or greater, systolic blood pressure of less than 90 mm Hg or diastolic blood pressure of 60 mm Hg or less, and age of at least 65 years; EEG, electroencephalogram; GCS, Glasgow Coma Scale; Hkt, hematocrit; ICDSC, Intensive Care Delirium Screening Checklist; N.O., nitric oxide; NS, not significant; PSI, pneumonia severity index; RR, blood pressure; sO2, blood oxygen saturation.