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. Author manuscript; available in PMC: 2013 Jun 13.
Published in final edited form as: Pediatr Crit Care Med. 2011 Nov;12(6):e369–e375. doi: 10.1097/PCC.0b013e3181fe40a7

Figure 2.

Figure 2

Effect of photothrombosis (PTI) on CBF (ml/min.100g) during normotension at 1 and 4h post insult and hypotension at 2.5 hr post insult in the ipsilateral and contralateral cortex in the absence and presence of tPA (2mg/kg iv), RBC-tPA (0.1 mg/kg iv), U 0126, SB 203580, SP 600125, or D-JNKI1 (all 1 mg/kg iv), n=5. Drugs are given either 30 min prior to or 2h after photothrombosis, designated as pre and post treatment (30 min prior or 2h post insult). *p<0.05 versus corresponding 0 time value +p<0.05 versus corresponding PTI alone value #p<0.05 versus corresponding PTI alone normotension value.