Table 2. Cox univariate and multivariate analysis of OS in DLBCL patient's training cohort (n=414).
The prognostic factors were tested as single variable (A) or multivariables (B, C) using Cox-model. P-values and the hazard ratios (HR) are shown. NS: not significant at a 5% threshold.
| A. | Overall survival (n=414) | |
|---|---|---|
| Prognostic variable | HR | P value |
| GERS | 4.62 | <.0001 |
| Age (>60 years) | 2.2 | <.0001 |
| GCB-ABC molecular subgroups | 2.75 | <.0001 |
| IPI | 1.79 | <.0001 |
| B. | Overall survival (n=414) | |
|---|---|---|
| Prognostic variables compared two by two | HR | P value |
| GERS | 4.25 | <.0001 |
| Age (>60 years) | 1.82 | <.0001 |
| GERS | 3.75 | <.0001 |
| GCB-ABC molecular subgroups | 1.51 | .03 |
| GERS | 4.60 | <.0001 |
| IPI | 1.83 | <.0001 |
| C. | Overall survival (n=414) | |
|---|---|---|
| All prognostic variables | HR | P value |
| GERS | 4.11 | <.0001 |
| Age (>60 years) | 1.26 | NS |
| GCB-ABC molecular subgroups | 1.27 | NS |
| IPI | 1.74 | <.0001 |