Table 1.
Baseline Patient Characteristics
| Baseline Patient Characteristics | |||
|---|---|---|---|
| Steroid-free | Steroid-based | P value | |
| N | 60 | 70 | |
| Recipient | |||
| Mean age (yrs)(median; range) | 11.8 ± 5.4(12.7; 1.5–19.9) | 11.9 ± 6.1 (11.9; 1.0–20.3) | 0.93 |
| Infant: ≤ 5 yrs old (%) | 18.3% | 21.4% | 0.66 |
| 5–12 years old (%) | 30.0% | 22.9% | 0.36 |
| >12 years old (%) | 51.7% | 55.7% | 0.64 |
| Mean age (yrs) males | 11.3 ± 5.5 | 12.1 ± 6.6 | 0.55 |
| Mean age (yrs) females | 12.9 ± 5.2 | 11.6 ± 5.4 | 0.42 |
| Gender: females (%) | 33% | 40% | 0.43 |
| Mean height (cm)(median; range) | 137.6 ± 26.5 (143; 75.8–183) | 136.0 ± 33.3 (143; 71.0–183) | 0.77 |
| Height Z-score | −1.2 ± 1.4 | −1.3 ±1.3 | 0.70 |
| Mean weight (kg)(median; range) | 40.2 ± 18.9 (40.6; 10–85) | 40.7 ± 22.9 (41.3; 8.8–113) | 0.86 |
| Mean BMI (kg/m2) | 19.9 ± 4.1 | 20.0 ± 4.1 | 0.90 |
| Mean BSA (m2) | 1.2 ± 0.4 | 1.2 ± 0.5 | 1.00 |
| Race (1,2,3,4) † | 55%, 25%, 8%, 12% | 50%, 27%, 4%, 19% | 0.56 |
| CMV D+R− | 46.7% | 42.9% | 0.66 |
| EBV D+R− | 13.3% | 11.4% | 0.74 |
| Transfusions 0, 1–5, >5, unknown (%) | 48.3, 40.0%, 6.7%, 5.0% | 64.3%, 24.3%, 8.6%, 2.9% | 0.08 |
| Dialysis mode pre-transplant (none, hemodialysis, peritoneal dialysis, both) | 20%, 36.7%, 20.0%, 23.3% | 14.3%, 41.4%, 21.4%, 22.9% | 0.39 |
| Cold ischaemia time (mins) | 705.1 ± 479.1 | 716.6 ± 416.5 | 0.90 |
| Cause of ESRD (1,2,3,4,5,6,7,8)* | (8%,3%,18%,2%,12%,15%,3%,38%) | (10%,1%,16%,11%,11%,9%,9%,33%) | 0.33 |
| Mean eGFR (ml/min 1.73 m2) | 14.2 ± 9.6 | 13.8 ± 8.1 | 0.81 |
| Mean Hematocrit (%) | 33.9 ± 6.4 | 34.4 ± 6.8 | 0.71 |
| Mean white cell count (ul) | 8.7 ± 3.9 | 7.8 ±2.8 | 0.12 |
| Mean serum cholesterol (mg/dl) | 160.8 ± 40.2 | 148.5 ± 40.9 | 0.12 |
| Mean serum triglyceride (mg/dl) | 177.1 ± 89.7 | 164.8 ± 109.9 | 0.53 |
| Mean Systolic blood pressure (mmHg) | 126.4 ± 19.4 | 122.7 ± 20.3 | 0.30 |
| Mean Diastolic blood pressure (mmHg) | 74.7 ± 15.9 | 72.1 ± 15.4 | 0.35 |
| Donor | |||
| Mean donor age (median; range) | 29.1 ± 10.1 (28.5; 2–47) | 27.4 ± 10.0 (26.5; 5–54) | 0.34 |
| Gender: females (%) | 47% | 40% | 0.44 |
| Donor Type (LRD) | 40% | 34% | 0.59 |
| Mean HLA match LRD | 2.5 ± 1.9 | 1.9 ±1.4 | 0.06 |
| Mean HLA match DD | 0.6 ± 0.9 | 0.7 ± 0.8 | 0.85 |
†
1=White; 2=Black/African American; 3=Asian; 4=Other
*
1=glomerulonephritis; 2=polycystic kidney disease; 3=dysplasia; 4=reflux nephropathy; 5=obstructive uropathy; 6=FSGS; 7=congenital nephrotic syndrome; 8=others