Table 1.
Baseline characteristics
| Characteristic | Carriers (n = 22) | Controls (n = 22) | P value |
|---|---|---|---|
| Age (years) | 42.5 ± 12.2 | 42.8 ± 13.4 | ns |
| Male sex, n (%) | 11 (50) | 11 (50) | ns |
| Height (cm) | 168 ± 11 | 171 ± 11 | ns |
| Weight (kg) | 65.7 ± 16.2 | 77.1 ± 13.4 | ns |
| BMI (kg/m2) | 23.1 ± 5.1 | 26.6 ± 4.8 | ns |
| Body surface area (m2) | 1.74 ± 0.23 | 1.84 ± 0.19 | ns |
| Diabetes, n (%) | 11 (50) | 0 (0) | N/A |
| Hypertension, n (%) | 5 (23) | 0 (0) | N/A |
| Cardiac parameters | |||
| Sinus rhythm, n (%) | 24 (100) | 24 (100) | ns |
| Heart rate (min−1) | 77 ± 13 | 59 ± 9 | <0.0001 |
| SBP (mmHg) | 116 ± 13 | 123 ± 11 | ns |
| DBP (mmHg) | 77 ± 8 | 75 ± 9 | ns |
| Selected medications | |||
| ACE inhibitor/ARB | 9 (41) | 0 (0) | N/A |
| Beta blocker | 2 (9) | 0 (0) | N/A |
| Calcium channel blocker | 2 (9) | 0 (0) | N/A |
| Statin | 8 (36) | 0 (0) | N/A |
| Insulin | 6 (27) | 0 (0) | N/A |
ns, not significant (P > 0.05); N/A, not applicable; SBP, systolic blood pressure; DBP, diastolic blood pressure; ACE, angiotensin-converting enzyme; ARB, angiotensin receptor blocker; BMI, body mass index.