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. 2013 Jun 10;12:55. doi: 10.1186/1476-4598-12-55

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Copyright © 2013 Ji et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Antiproliferative effect of FKB on OS cells. A, Four OS cell lines and fibroblast cell line (HESC) were used and cells were treated with FKB at the indicated concentration in the figure for 72 h, and cell viabilities were measured by MTT assay. B, 143B cells were treated with indicated concentrations for 24, 48 or 72 h. C, anchorage-independent colony formation assay showed significantly decreased number of colonies formed by 143B cells treated with FKB compared with control group; inset, representative photography of soft agar colonies at 14 days after cell seeding. An asterisk (*) indicates a significant difference in comparison with the control group (p<0.05).