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. 2013 Jun 10;12:55. doi: 10.1186/1476-4598-12-55

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Copyright © 2013 Ji et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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FKB showed preferential inhibition on 143B cells compared with FHS and bone marrow stem cells. A, FKB treatment exhibited differential effects on 143B OS cells, normal small intestinal epithelial cell (FHS) and bone marrow stem cells. Cells were treated with FKB for 72 h. B, Compared with Adriamycin, FKB showed significantly less bone marrow inhibition effect. C, Representative microphotography, taken at 14 days after treatment of bone marrow stem cell colonies showed the size of a typical colony decreased with a higher concentration of FKB.