Table 3. Predicted horizontally transferred genes that may be associated with pathogenesis in Saprolegnia parasitica.
| Pfam function | Functional Description | Possible Phylogenetic origin | Number Genes in the family | Representative gene ID | Subcellular Localizationa | HGT time Estimateb |
| Disintegrin | Disintegrin | proteobacteria | 16 | SPRG_14051 | secreted | recent |
| Laminin like | Associated with cell surface | - | 1 | SPRG_08424 | secreted | recent |
| CHAP | CHAP domain | - | 7 | SPRG_15528 | secreted | |
| Endonuclease | DNA/RNA non-specific endonuclease | bacteria | 6 | SPRG_08128 | secreted | |
| HylE | Haemolysin E | enterobacteria | 9 | SPRG_04818 | membrane | recent |
a
Subcellular localization is predicted by the N-terminal signal peptide, mitochondrial targeting motif and transmembrane domains.
b
The time of horizontal gene transfer is estimated by the presence in other oomycetes and coding potential of a given gene. ‘a recently acquired gene’ refers to a gene occurring only in Saprolegnia and having an uncharacteristic coding potential.