Figure 5. IDO attenuates influenza-specific CD8 T cell responses in X31-infected mice.

A–C. B6 and IDO1-KO (B6) mice were infected with X31 virus and total numbers of cells and virus-specific CD8 T cell numbers were evaluated in msLNs at 10 dpi using tetramers specific for NP₃₆₆ (B) and PA (C). Data were compiled from 5 experiments, and statistical analyses were performed using Student's unpaired t test; **p<0.01, ***p<0.001.