Figure 2. α2 adrenoceptors contribute to NE-induced persistent firing.
(A) NE-induced persistent firing was partially suppressed by the selective α2 adrenoceptor antagonist yohimbine (Yohim, 10 µM; n = 6). (C) NE-induced persistent firing was not affected by the βadrenoceptor antagonist propranolol (Prop, 10 µM; n = 9). (B) and (D) Quantitative effects of yohimbine and propranolol on firing frequency and amplitude of plateau potentials. Values are mean ± SEM. ** p<0.01.