Table 2.
ROI analysis of GM volumes and results of mediation analyses.
| (A) Correlations between GM volumes and drinking variables: Spearman regression. | |||
|---|---|---|---|
| ROI | Frequency/month | Drinks/time | Drinks/month |
| Left PCG (n=113) | r = 0.29 (p<0.0017) | r = 0.39 (p<1.6e-05) | r = 0.35 (p<0.0001) |
| Left SFG (n=66) | r = 0.27 (p<0.0286) | r = 0.35 (p<0.0040) | r = 0.32 (p<0.0081) |
| Right SFG (n=66) | r = 0.01 (p<0.9594) | r = 0.15 (p<0.2414) | r = 0.04 (p<0.7598) |
| Right ventral putamen (n=47) | r = −0.25 (p<0.0957) | r = 0.08 (p<0.6069) | r = −0.14 (p<0.3627) |
| (B) Mediation analysis results between alcohol expectancy (AE), drinking variables and GM volumes. | |||||
|---|---|---|---|---|---|
| Mediation models | Path a (X→M) | Path b (M→Y) | Path c′ (X→Y) | Mediation path a*b | |
| Model 1 (n=113) | β | 0.40 | 0.03 | 0.30 | - |
| X (AE) → Y (Freq./month) mediated by M (left PCG) | p | 0.0005* | 0.7656 | 0.0007* | 0.7297 |
|
| |||||
| Model 2 (n=113) | β | 0.40 | 0.26 | 0.25 | - |
| X (AE) → Y (Drinks/time) mediated by M (left PCG) | p | 0.0006* | 0.0088* | 0.0107* | 0.0060* |
|
| |||||
| Model 3 (n=113) | β | 0.29 | 0.34 | 0.24 | - |
| X (AE) → Y (Drinks/month) mediated by M (left PCG) | p | 0.0028* | 0.0008* | 0.0085* | 0.0010* |
|
| |||||
| Model 4 (n=66) | β | 0.53 | 0.04 | 0.54 | - |
| X (AE) → Y (Drinks/time) mediated by M (left SFG) | p | 0.0000* | 0.5754 | 0.0064* | 0.5171 |
β denotes the regression coefficients and p values are uncorrected. The mark “*” indicates p<0.05, Bonferroni corrected (p=0.05/4=0.0125).