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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2013 Mar 14;12(6):890–900. doi: 10.1158/1535-7163.MCT-12-0998

Figure 3. Immunoblot evaluation evaluating effects of NVP-AUY922 in vitro.

Figure 3

Immunoblot evaluation for cell lines with IC50 < 5 nM and IC100 < 40 nM (A), IC50 > 5 nM and IC100 < 40 nM (B) and IC100 > 40 nM (C) are shown. Measured proteins include HSP70, pERK 1/2 (Thr202/Tyr204), total ERK1/ERK2, pAKT (Ser473/Ser308), total AKT, and Tubulin at baseline and after 30 minutes, 18 and 24 hours of treatment with 50 nM or 100 nM of NVP-AUY922 as indicated.