Figure 6. Association of PD-L1/PTEN expression with overall survival (OS) and metastasis-free survival (MFS) in 347 CRC patients.
(A, B) The OS and MFS were significantly lower in PD-L1-higher-expression patients compared with PD-L1-lower-expression patients (both P<0.001). (C, D) The OS and MFS were not significantly different between the PTEN-higher-expression patients and the PTEN-lower-expression patients (OS, P = 0.366; MFS, P = 0.141). (E) In the subset of 39 patients with complete PTEN loss, PD-L1 expression was no longer associated with the OS (P = 0.482).