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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Tuberculosis (Edinb). 2013 Mar 28;93(4):432–441. doi: 10.1016/j.tube.2013.02.009

Figure 4. Quantification of the T cells in blood and tissue.

Figure 4

A) The absolute number of cells that positively stain for CD3, CD8 and CD4 expression in granulomatous tissue from one region of interest (×40 magnification) per HIV-negative and -positive patient. Results are the median and the error bars indicate the IQR. B) The ratio of CD4:CD8 T cells in the peripheral blood (circles) and in the infected tissue (squares) of the patient cohort. Closed symbols: HIV-negative samples and open symbols: HIV-positive samples. * p < 0.05, ** p < 0.01, *** p < 0.005 by two-tailed t-test.