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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Tuberculosis (Edinb). 2013 Mar 28;93(4):432–441. doi: 10.1016/j.tube.2013.02.009

Figure 6. Pathological features of Spinal TB infection.

Figure 6

A – D) Granuloma formation within a nerve bundle (n), surrounded by connective tissue, from an HIV-negative patient. Blood vessel (v). A) H&E staining. Immunostaining for CD68 (B), CD3 (C) and CD4 (D). (×10 magnification). E – H) Evidence of fibrosis (f) in an HIV-negative (E, F) and an HIV-positive (G, H) specimen. E, G) H&E staining. F, H) CD68 immunostaining, marking the presence of multinucleated giant cells (g) and scattered, individual macrophages (arrows) (×40 magnification).