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. Author manuscript; available in PMC: 2014 Feb 5.
Published in final edited form as: Chem Rev. 2012 Oct 11;112(12):6388–6430. doi: 10.1021/cr300141q

Figure 5.

Figure 5

A: The effect of symmetrical addition of polyethylene glycol (PEG) of different molecular weights in 15% w/w concentration on the ion current through a single ETX channel. It is seen that PEGs not only change the average conductance but, depending on molecular weight, induce significant fluctuations. B and C: Experiments performed under asymmetrical PEG additions demonstrate that these fluctuations are mostly caused by permeant PEGs added to the trans side of the membrane. Time resolution was 0.1 ms, transmembrane voltage −100 mV. Reprinted with permission from ref58. Copyright 2010. Biophysical Society.