Table 2.

Combined CYP3A4/5 genotype and dose levels.

		Poor metabolizers per dose level			Intermediate metabolizers per dose level			Extensive metabolizers per dose level
	n	≤10 mg	20 mg	≥40 mg	≤10 mg	20 mg	≥40 mg	≤10 mg	20 mg	≥40 mg
Atorvastatin	142	5 (45%)	4 (36%)	2 (18%)	27(27%)	28 (28%)	46 (46%)	5(17%)	11(37%)	14 (47%)
Simvastatin	84	2(29%)	3 (43%)	2 (29%)	4 (7%)	18 (31%)	36(62%)	2(11%)	6 (32%)	11 (58%)

Data for each dose level represents the number of patients and percentage of the combined genotype group at the specified dosing level.