Table 1.
Demographic data, and baseline clinical characteristics of the 46 post-cardiac-arrest patients, including the survivors, and non-survivors
| Parameters | All patients | Survivors | Non-survivors | p valuea |
|---|---|---|---|---|
| No. of patients | 46b | 24 | 22 | |
| Age (years), median (IQR) | 64 (56–69)c | 57 (47–66) | 66 (6–-69) | 0.0141 |
| Males/females | 38/8 | 20/4 | 18/4 | 1.0000 |
| OHCA/IHCA | 36/10 | 17/7 | 19/3 | 0.2894 |
| Body mass index (kg/m2), median (IQR) | 27.8 (24.6–31.0) | 27.8 (26.0–29.4) | 25.9 (24.2–31.1) | 0.7193 |
| Simplified Acute Physiology Score II, median (IQR) | 61 (55–69) | 56 (51–70) | 64 (60–68) | 0.0293 |
| Acute Physiology and Chronic Health Evaluation II, median (IQR) | 29 (25–32) | 27 (25–29) | 32 (28–34) | 0.0115 |
| Time from collapse until the start of ALS/BLS (min), median (IQR) | 1 (0–6) | 1 (0–5) | 1 (0–9) | 0.6268 |
| Time from the collapse until the ROSC (min), median (IQR) | 21 (15–30) | 20 (15–30) | 28 (18–30) | 0.2548 |
| Total duration of CPR (min), median (IQR) | 20 (12–28) | 19 (12–22) | 21 (13–30) | 0.4926 |
| No. of patients requiring further support in another ICU | 16 | 5 | 11 | 0.0626 |
| EF (%), median (IQR) | 35 (28–45) | 36 (31–47) | 31 (25–40) | 0.1632 |
| Body temperature at baseline (°C), median (IQR) | 36.4 (35.8–36.6) | 36.5 (36.1–36.6) | 36.3 (35.3–36.6) | 0.4697 |
| Body temperature at 6 h (°C), median (IQR) | 32.7 (32.0–33.0) | 32.8 (32.5–33.0) | 32.0 (32.0–33.9) | 0.1093 |
| Body temperature at 24 h (°C), median (IQR) | 32.5 (32.1–33.0) | 32.7 (32.4–33.0) | 32.3 (32.1–32.8) | 0.1143 |
| Minimum temperature during the initial 24 h (°C), median (IQR) | 31.9 (31.6–2.6) | 32.2 (31.7–32.7) | 31.8 (31.6–32.0) | 0.0490 |
| No. of patients requiring catecholamine therapy | 29 | 10 | 19 | 0.0972 |
| No. of patients requiring combined catecholamine therapy | 16 | 5 | 11 | 0.1159 |
| No. of patients with cardiogenic shock requiring IABP therapy | 19 | 6 | 13 | 0.0349 |
| Total, 24-h urine output (ml), median (IQR) | 3,410 (2,450–4,130) | 3,510 (3,185–4,610) | 2,950 (1,900–4,070) | 0.0513 |
| Sepsis, no. of cases | 9 | 3 | 6 | 0.2757 |
| Infection as a complication, no. of cases | 22 | 13 | 9 | 0.3945 |
| Bleeding as a complication, no. of cases | 10 | 2 | 8 | 0.0323 |
| Ischemic complications, no. of cases | 6 | 0 | 6 | 0.0080 |
| S100B >200 pg/ml during the initial 24 h, N | 11 | 2 | 9 | 0.0149 |
| Delayed hypothermia (time from collapse until the start of hypothermia (h), median (IQR) | 3.7 (2.7–4.5) | 3.6 (2.5–4.5) | 4.1 (3.0–4.5) | 0.2941 |
| CPC I or II at discharge | 19 | 17 | 2 | 0.0039 |
IQR interquartile range, OHCA out-of-hospital cardiac arrest, IHCA in-hospital cardiac arrest, ALS advance life support, BLS basic life support, ROSC return of spontaneous circulation, EF ejection fraction, CPC Cerebral Performance Categories Scale, S100B biochemical marker of brain cell damage
aMann–Whitney test (continuous variables) or Pearson’s chi-square test (categorical variables) between survivors and non-survivors
bNumber of cases
cMedian values with interquartile ranges