Fig. 4.

Force-generating capacities of leg muscles from Zmpste24^+/+and Zmpste24^−/− mice from 15 to 20 weeks of age. a Maximal isometric torque of muscle groups of the leg. b Maximal isometric force (P_o) of isolated leg muscles. Normalized torque is maximal torque relative to the sum of respective muscle masses. Specific P_o is maximal isometric tetanic force relative to physiological cross-sectional area of the muscle. Data are shown relative to Zmpste24^+/+mice and presented as means ± SE; n = 3 to 14 per genotype. Asterisk, significantly different than Zmpste24^+/+mice