Table 2.

Masses and content of leg muscles of Zmpste24^+/+ and Zmpste24^−/− mice

	Zmpste24+/+	Zmpste24−/−	p value
Muscle mass (mg/g) (n)	(25)	(16)
Extensor digitorum longus	0.38 ± 0.02	0.47 ± 0.02	0.003
Tibialis anterior	1.74 ± 0.09	1.82 ± 0.13	0.588
Soleus	0.33 ± 0.03	0.36 ± 0.01	0.322
Gastrocnemius	5.25 ± 0.28	5.15 ± 0.13	0.772
Collagen content (μg/mg) (n)	(8–13)	(3–13)
Extensor digitorum longus	10.7 ± 2.3	17.2 ± 2.0	0.005
Tibialis anterior	17.4 ± 0.5	27.4 ± 2.5	<0.001
Soleus	17.8 ± 3.2	30.6 ± 2.5	<0.001
Gastrocnemius	19.2 ± 2.3	27.8 ± 1.2	<0.001

Mean ± SE. Muscle masses normalized to body mass. Collagen contents normalized to muscle masses