Table 1.
Baseline characteristica | Daptomycin 4 mg/kg qd (n = 88) | Vancomycin 1 g bid (n = 22) |
---|---|---|
Age (years), median (range) | 69.0 (22–92) | 70.0 (29–82) |
Gender (male) | 47 (53.4) | 15 (68.2) |
Bodyweight (kg), median (range) | 54.00 (28.3–117.8) | 52.25 (36.5–78.3) |
CLcr (ml/min), median (range) | 78.14 (23.1–260.8) | 78.17 (37.7–153.7) |
<30 | 1 (1.1) | 0 (0.0) |
≥30 to <50 | 17 (19.3) | 5 (22.7) |
≥50 to <80 | 28 (31.8) | 7 (31.8) |
≥80 | 41 (46.6) | 10 (45.5) |
Prior anti-MRSA antibioticsb | 10 (11.4) | 2 (9.1) |
qd once daily, bid twice daily, CLcr creatinine clearance, MRSA methicillin-resistant Staphylococcus aureus
aUnless otherwise specified, values are expressed as n (%)
bAnti-MRSA agent used within 28 days before the start of study drug administration