Figure 2.

Effects of encounter stimulation on c-Fos expression in the prefrontal cortex (a), nucleus accumbens shell (b) and core (c), the medial (d) and basolateral (e) amygdala, dorsal raphe nucleus (f), and ventral tegmental area (g) of mice. Immunohistochemical localization of the neuronal-activity-marker c-Fos in the male group- and isolation-reared mice was determined 2 h after the encounter. Mice that were not exposed to an intruder were used as controls. The data are expressed as the mean±SEM of 8 mice/group. *p<0.05, **p<0.01, compared with the control. †p<0.05, compared with the encounter stress-challenged group-reared mice.