Table 1. Noradrenaline (NE), Serotonin (5-HT) and its Metabolite, 5-Hydroxyindole-3-Acetic Acid (5-HIAA), Content in mPFC, Dorsal Striatum, and Nucleus Accumbens of Vehicle- (Control) and Quinpirole-Treated (QUIN) Rats.
| Control (ng/mg tissue) | QUIN 0.1 (ng/mg tissue) | QUIN 0.5 (ng/mg tissue) | |
|---|---|---|---|
| mPFC | |||
| NE | 304±36 | 238±19 | 288±60 |
| 5-HT | 308±22 | 271±39 | 272±39 |
| 5-HIAA | 211±17 | 174±32 | 205±27 |
| Striatum | |||
| 5-HT | 237±12 | 258±19 | 196±16 |
| 5-HIAA | 171±10 | 181±14 | 170±17 |
| NAc | |||
| 5-HT | 582±103 | 638±80 | 545±116 |
| 5-HIAA | 186±19 | 200±33 | 201±24 |
All data are expressed as ng of neurotransmitters per g of brain tissue (mean±SEM). n=5 per group.