Figure A2.

The determination of the first fate is reversible. Only the nodes whose activity changes dynamically are included, and the time at which they change is highlighted in yellow. (A) Transition from VPC to the first fate. The final pattern, which corresponds to the first fate is colored in blue. Also included in this figure, as the LS P column, are the effects of the addition of DSL ligands to the environment at different stages of first fate determination, if the DSL ligands are added before the eighth step, the VPC acquires the second fate instead of the first, if the environment changes at the eighth step, the VPC acquires a fate that cycles between an incomplete first fate and an incomplete second fate, if the DSL ligands are added to the environment after the eight step, the VPC acquires the first fate. (B) Transition from the first fate to VPC. The final pattern, which corresponds to the VPC is colored in orange.