Table A4.
The simulated effect of removing each interaction.
| Case | 1 | 2 | VPC | F | Muv | Vul | Egl | Wild type | Interactions |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | |
| 2 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | |
| 3 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | |
| 4 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | |
| 5 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | |
| 6 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | |
| 7 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | CEH-20 to HOXCO, HOXCO to LIN-39a, LET-23ML to LET-23, LET-23 to SEM-5, LET-60 to LIN-45, LIN-10 to LET-23M, LIN-1 to PJW5, LIN-25 to MC, LIN-2 to LET-23, LIN-39a to LIN-39, LIN-39 to LIN-39a, LIN-3* to LET-23, LIN-45 to MEK-2, LIN-7 to LET-23ML, MC to LIN-39, MEK-2 to MPK-1, MPK-1 to LIN-25, MPK-1 to LIN-39A, MPK-1 to PJW-5, MPK-1 to SUR-2, PJW5 to LIN-39, SEM-5 to SOS-1, SOS-1 to LET-60, SUR-2 to MC, UNC-62 to HOXCO |
| 8 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | LIT-1 to POP-1, MIG-5 to APR-1, POP-1b to LIN-39, POP-1 to POP-1b, WRM-1 to POP-1 |
| 9 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | |
| 10 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | |
| 11 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | CSL to LIN-11, CSL to LIP-1 |
| 12 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | |
| 13 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | |
| 14 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | LIN-39 to REF-2, REF-2 to EFF-1 |
| 15 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | APX-1* to LS, CWN-1* to LIN-17, CWN-1* to MOM-5, CWN-2* to LIN-17, CWN-2* to LIN-18, DSL-1* to LS, EGL-20* to CAM-1, EGL-20* to MOM-5, LAG-2* to LS, LIN-44* to LIN-17, LIN-44* to MIG-1, MOM-2* to LIN-18, MOM-2* to MIG-1, APH-1 to APH-2, APH-1 to SEL-12, APH-2 to SEL-12, APR-1 to GSK-3, APR-1 to KIN-19, APR-1 to PRY-1, ARK-1 to LET-23, BAR-1 to POP-1B, CAM-1 to WRM-1, CEH-13 to HOXCO, CSL to ARK-1, CSL to DPY-23, CSL to EFF-1, CSL to LAG-1, CSL to LIN-12, CSL to LST-1, CSL to LST-2, CSL to LST-3, CSL to LST-4, CSL to MIR-61, EGL-18 to EFF-1, EGL-20* to MAB-5, ELT-6 to EFF-1, GAP-1 to LET-60, GSK-3 to BAR-1, GSK-3 to SYS-1, GSK-3 to WRM-1, KIN-19 to GSK-3, KSR-1 to MEK-2, KSR-2 to MEK-2, LAG-1 to CSL, LET-60 to RGL-1, LIN-12_1 to LIN-12_2, LIN-12_2 to LIN-12_3, LIN-12_3 to CSL, LIN-12 to LIN-12_1, LIN-14 to LIN-12_1, LIN-17 to MIG-5, LIN-17 to WRM-1, LIN-18 to WRM-1, LIN-31 to PJW-5, LIN-39a to EGL-17, LIN-39a to EGL-18, LIN-39a to ELT-6, LIN-39a to LAG-2, LIN-39a to LIN-12, LIN-39 to HOXCO, LIN-4 to LIN-14, LIP-1 to MPK-1, LS to LIN-12_1, MAB-5 to HOXCO, MC to APX-1, MC to DSL-1, MC to LAG-2, MC to LIN-12_1, MIR-61 to VAV-1, MOM-5 to MIG-5, PEN-2 to SEL-12, PRY-1 to GSK-3, RAL-1 to CSL, RGL-1 to RAL-1, SEL-12 to LIN-12_3, SEL-8 to CSL, SEM-5 to ARK-1, SUP-17 to LIN-12_2, SYS-1 to POP-1b, VANG-1 to CAM-1, VAV-1 to LIN-12_1, vpcwt23h |
| 16 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
For each interaction removed, we obtained the cellular fates that are represented by the attractors, based on this we classified the interactions using the procedure described in the caption of Table A2.