Fig. 1.

Mean ganglion complex thickness as measured by optical coherence tomography. The mean ganglion complex thickness was significantly lower in the group of Gaucher disease patients and GBA mutation carriers who had clinical markers of potential early neurodegeneration (bar marked neurological sign present) than in the control group or the group of Gaucher disease patients and carrier without clinical markers of potential early neurodegeneration (bar marked no neurological sign). Above each bar is a representative heat map of the optical coherence tomography studies. Red areas represent ganglion complex thickness less than 1% of predicted for age and sex, yellow areas less than 5% of predicted and green areas thickness greater than 5% of predicted. The grey disc represents the fovea.