Fig. 5.

CG MD simulation system with an ENTH-lattice‐coated membrane tubule. (a) A membrane tubule is shown in gray. Red lines connect CG sites. Selected CG sites are shown in sphere representation. H₀ and hydrophobic contact sites V50 and V51 are shown in blue and white spheres, respectively. (b) Close-up of (a). (c) Close-up ribbon view of the ENTH tetramer in (b). Four ENTH domains are shown in red ribbons, while H₀ helices are shown in thicker blue ribbons. Hydrophobic contact patches, V50 and V51, are shown as white spheres. (d) Bottom view of (c), with only a dimer unit shown. L6 and M10 are shown in cyan spheres. The orange and light blue arrows represent the measured EPR distance (~ 13 Å) for L6 and M10, respectively. (e) Bottom view of (c). Offset packing between two dimers that brings the I13 and V14 region of H₀ in close proximity as highlighted with a yellow arrow. I13 and V14 are shown in sphere representation. This is indicated by an EPR distance profile of 15 Å for I13 and 10 Å for V14. These distances are shorter than would be expected for an antiparallel dimer pairing.