Fig. 6.

(a) Close-up view of the ENTH domain lattice on a type A tube. Selected defect sites are shown with yellow arrows. Lipids are shown in gray. CG sites are shown as red spheres, except for H₀ sites that are shown in blue spheres and PIP₂ interaction sites that are shown in cyan. (b) Local orientational order of ENTH domain-bound membrane tube (type B tube). The simulation snapshot is colored to show the local orientational order in the neighborhood of each ENTH domain. The color scale reflects the average of the unsigned dot product between the H₀ axes of neighboring ENTH domains within 5 nm. Blue corresponds to a high degree of local order, and red corresponds to local disorder. There is considerably more disorder for both the capping regions, and the defect sites are scattered across the tube in a nonuniform manner. Selected defect sites are highlighted in yellow dashed circles. (c) Local orientational order parameter color map of an ENTH domain-bound membrane vesicle. The representative simulation snapshot is taken from an equilibrated CG MD simulation.