Treatment Characteristics	Estimates
Remission	45 out of 100 patients go into remission
	25 out of 100 patients go into remission
	15 out of 100 patients go into remission
Improvement	70 out of 100 patients feel much better, but occasionally have some joint pain or swelling
	50 out of 100 patients feel much better, but occasionally have some joint pain or swelling
	40 out of 100 patients feel much better, but occasionally have some joint pain or swelling
Radiographic progression	No further bone damage seen on X-rays in 80 out of 100 patients
	No further bone damage seen on X-rays in 50 out of 100 patients
	No further bone damage seen on X-rays in 30 out of 100 patients
Route	Pill you take once a week
	Injection you give yourself once every 1-2 weeks
	Intravenous infusion you get every 6-8 weeks
Injection reaction	No injection reactions
	30 in 100 patients get a rash or local burning at the site of injection
	3 in 100 patients will get a reaction during the infusion (headache, nausea, fever)
Reversible adverse events	No increased risk of nausea, dizziness or unusual tiredness
	10 in 100 people will have nausea, dizziness or unusual tiredness
Risk of lung injury	No increased risk of lung or liver injury
	Rare risk of lung injury (about 2 in 100 patients) or liver injury (about 1 in 1000 patients)
Risk of tuberculosis	No increased risk of tuberculosis
	Extremely rare risk of tuberculosis (about 1 in 10,000 patients)
Extremely rare adverse events	No increased risk of neurologic disease or heart failure
	Extremely rare risk of neurologic disease or heart failure (about 1 in 10,000 patients)
Risk of cancer	No increased risk of cancer
	Possible increased risk of cancer (about 1 in 1000 patients)